Recent Publications
LGR4 mutations disrupt WNT signaling to influence CYP11B2 and aldosterone production
Journal of Clinical Investigation
Analysis of CYP21A2 mutations in congenital Adrenal Hyperplasia
Frontiers in Pharmacology
Loss of Protein Stability and Function Caused by P228L Variation in NADPH Cytochrome P450 Reductase Linked to Lower testosterone Levels
IJMS
Non-steroidal CYP17A1 Inhibitors: Discovery and Assessment.
J Med. Chem
DOI: 10.1021/acs.jmedchem.3c00442
Upcoming presentations at conferences
Some recent and upcoming conferences with presentations from Pandeylab members
Katyayani Sharma
IMPE, Buenos Aires, Argentina. March 2023
Targeting androgen production by post-translational regulation of CYP17A1 lyase activity.
Natalia Rojas
IMPE, Buenos Aires, Argentina. March 2023
Mutation V631I in the Cytochrome P450 oxidoreductase (POR) alters steroid biosynthesis and drug metabolism.
Amit V Pandey
IMPE, Buenos Aires, Argentina. March 2023
PDE5 inhibitors may reverse the effects of isolated growth hormone deficiency caused by alternate splicing of the GH1 gene.
Amit V Pandey
IMPE, Buenos Aires, Argentina. March 2023
Inhibiting the binding of ACTH to the Melanocorticotropin receptor by peptide to block androgen production.
Suleiman Ibrahim
At 2023 at 15th International Symposium on Cytochrome P450 - Biodiversity and Biotechnology, 27 to 30 June 2023
Katyayani Sharma
At ASPET 2023 Annual Meeting, St Louis, MO USA
18th to 21st May 2023
Natalia Rojas
AT ASPET 2023 Annual Meeting, St. Louis, MO, USA
18th to 21st May 2023
Amit Pandey
At ASPET 2023, St Louis MO USA,
On binding of ACTH to MC2R for treatment of Congenital Adrenal Hyperplasia
Katyayani Sharma
At LS2 Annual Meeting, Zurich Switzerland. 15th to 17th February 2023
Some of the recent awards, grants and scholarships won by members of PandeyLab
Grants
Project Grant: Swiss National Science Foundation
Regulation of Metabolism Conformational Changes in an Electron Transport Protein
Research Grant: Cancer Research Switzerland
Inhibitors of androgen biosynthesis for the treatment of castration-resistant prostate cancer.
Research Collaboration Grant: State Secretariat for Education, Research and Innovation, Switzerland
Role of CYP6Z1 in metabolism of insecticides and development of insecticide resistance in mosquitoes.
State Secretariat for Education, Research and Innovation, Switzerland
Role of POR mutations in human metabolism
Novartis Foundation for Medical Biological Research
Generation of personalized models of mutations in POR deficiency.
Bern University Research Foundation
Role of POR in metabolic Regulation and protein stability.
Katyayani Sharma
Dean of Medical Faculty COVID19 relief Award
Regulation of androgen biosynthesis in PCOS and prostate cancer.
Awards and Scholarship
Katyayani Sharma
Swiss Government Excellence Scholarship. 2019-2022
Maria Natalia Rojas Velazquez
Swiss Government Excellence Scholarship. 2020-2023
Jibira Yakubu
Swiss Government Excellence Scholarship. 2022-2025
Paul Ikwegbue
Swiss Government Excellence Scholarship. 2023-2026
Isabel Sousa Barata
Swiss Government Excellence Scholarship. 2023-2026
Dr. Shripriya Singh
Swiss Government Excellence Scholarship. 2020-2021
Dr. Mayara Jorgens Prado
Swiss Government Excellence Scholarship. 2020-2021
Maria Natalia Rojas Velazquez
Best Poster Award for PhD students at DBMR Annual Research Conference 2022