2011

42. Christa E. Flück, Monika Meyer-Böni, Amit V. Pandey, Petra Kempná, Walter L. Miller, Eugen J. Schoenle, and Anna Biason-Lauber. Why Boys will be Boys: Two Pathways of Fetal Testicular Androgen Biosynthesis Are Needed for Male Sexual Differentiation. Am J Hum Genet 89: 201-218 (2011).  http://dx.doi.org/10.1016/j.ajhg.2011.06.009

41. Christa E. Flück, Delphine Mallet, Gaby Hofer, Dinane Samara-Boustani, Juliane Leger, Michel Polak, Yves Morel, Amit V. Pandey. Deletion on P399_E401 in NADPH P450 oxidoreductase results in partial mixed oxidase deficiency. Biochem Biophys Res Commun  412: 573-577 (2011).  http://dx.doi.org/10.1016/j.bbrc.2011.08.001

40. Christa E. Flück, Amit V. Pandey , Bernhard Dick, Núria Camats, Mónica Fernández-Cancio, María Clemente3, Miquel Gussinyé, Antonio Carrascosa, Primus E. Mullis, Laura Audi. Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia. PLOS One 6 (5):e20178 (2011)

39. Pandey AV & Mullis PE. Molecular genetics and bioinformatics methods for diagnosis of endocrine disorders. In Diagnostics of Endocrine Function in Children and Adolescents.ISBN: 3805594143 (2011). S Karger AG; 4th Revised Edition. pp 32-52.

38. Petkovic V; Eble A; Pandey AV; Betta M; Mella P; Flück CE; Buzi F; Mullis PE. A novel GH-1 gene mutation (GH-P59L) causes partial GH deficiency type II combined with bioinactive GH syndrome. Growth Hormone & IGF Research  21: 160-166 (2011)

37. Flück CE, & Pandey AV. Clinical and biochemical consequences of P450 oxidoreductase deficiency. Endocr Dev. 20: 63-79 (2011).

36. Hirsch A, Audi L, Meimaridou E, Pandey AV, Clark, AJL and Flück, CE. Loss of the C-terminus of melanocortin receptor 2 (MC2R) results in impaired cell surface expression and ACTH insensitivity. J. Clin. Endocrinol. Metab. 96: 65-72 (2011)

2010

35. Flück CE, Mullis PE & Pandey AV. Reduction in hepatic drug metabolizing CYP3A4 activities caused by P450 oxidoreductase mutations identified in patients with disordered steroid metabolism. Biochem. Biophys. Res. Commun. 401: 149-153 (2010).

 
34. Pandey AV, Flück CE & Mullis PE. Altered heme catabolism by heme oxygenase -1 caused by mutations in human NADPH cytochrome P450 reductase. Biochem. Biophys. Res. Commun. 400: 374-378 (2010) 

33. Nicolo C, Flück CE, Mullis PE & Pandey AV. Restoration of mutant cytochrome P450 Oxidoreductase activity by external flavin. Mol Cell Endocrinol. 321: 245-252 (2010)

32. Petkovic V, Godi M, Pandey AV, Lochmatter D, Buchanan CR, Dattani MT, Eble A, Flück CE, Mullis PE. Growth Hormone (DH) Deficiency Type II: A Novel GH-1 Gene Mutation (GH-R178H) Affecting Secretion and Action. J. Clin Encocrinol. Metab. 95:731-739 (2010).

2009

31. Flück CE, Mullis PE, Pandey AV. Modeling Of Human P450 Oxidoreductase Structure By In Silico Mutagenesis And MD Simulation. Mol Cell Endocrinol. 313: 17-22 (2009)

30. Sim SC, Miller WL, Zhong XB, Arlt W, Ogata T, Ding X, Wolf CR, Flück CE, Pandey AV, Henderson CJ, Porter TD, Daly AK, Nebert DW, Ingelman-Sundberg M. Nomenclature for alleles of the cytochrome P450 oxidoreductase gene. Pharmacogenet Genomics. 19: 565-5666 (2009).

2008

29. Hooley, E, Papagrigoriou, E, Navdaev, A, Pandey, AV, Clemetson, JM, Clemetson, KJ. & Emsley, J. The Crystal structure of the platelet activator aggretin reveals a novel (ab)2 dimeric structure. Biochemistry, 47: 7831-7837 (2008)

28. Flück, CE, Pandey, AV, Huang, N, Agrawal, V & Miller WL. P450 oxidoreductase deficiency - a new form of congenital adrenal hyperplacia. Endocr Dev, 13: 67-81 (2008).

2007

27. Flück, CE., Nicolo, C & Pandey, AV. Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase Fundamental and Clinical Pharmacology, 21(4) 399-410 (2007).

26. Pandey, AV, Kempna, P, Hoffer, G, Mullis, PE & Flück, CE. Modulation of human CYP19A1 activity by mutant NADPH P450 oxidoreductase. Molecular Endocrinology, 21:2579-2595 (2007).

25. Carolina M. Pepe; Nora I. Saraco; Maria Sonia Baquedano;Gabriela Guercio, Elisa Vaiani; Roxana Marino; Amit V Pandey; Christa E. Flück; Marco A. Rivarola and Alicia Belgorosky The cytochrome P450 aromatase lacking exon 5 is associated with a phenotype of non-classic aromatase deficiency, and it is also present in normal human steroidogenic tissues. Clinical Endocrinology 67:698-705 (2007).

2006

24. Pandey AV. Biochemical analysis of mutations in P450 oxidoreductase. Biochemical Society Transactions. 34: 1186-1191 (2006).

23. Konrad, M, Schaller, A, Seelow, D, Pandey, AV., Siegfried Waldegger, Annegret Lesslauer, Helga Vitzthum, Yoshiro Suzuki, John M Luk, Christian Becker, Karl P Schlingmann, Marcel Schmid, Juan Rodriguez-Soriano, Gema Ariceta, Francisco Cano, Ricardo Enriquez, Harald Jueppner, Sevcan A Bakkaloglu, Matthias A Hediger, Sabina Gallati, Stephan CF Neuhauss, Peter Nürnberg, Stefanie Weber. Mutations in the tight junction gene claudin 19 (CLDN19) are associated with renal magnesium wasting, renal failure and severe ocular involvement. Am J Hum Genet 79:949-957 (2006).


22. Janer, M, Pandey, AV, Mullis, PE. and Fluck, CE. Clinical and biochemical description of a novel CYP21A2 gene mutation 962-963insA using a new 3D model for the P450c21 protein. Eur J. of Endocrinol. 155: 143-151 (2006).


2005

21. Pandey, AV and Miller, WL. Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17. J. Biol Chem. 280: 13265-13271 (2005) April 08, Cover Page.

20. Miller WL, Huang N, Pandey AV., Fluck CE, Agrawal V. P450 oxidoreductase deficiency: a new disorder of steroidogenesis.Ann N Y Acad Sci.1061:100-108 (2005).

19. Huang, N; Pandey, AV; Agrawal, V; Reardon, W; Lapunzina, PD; Mowatt, D; Okamjima, K; Jabs, EW; vanVliet, G; Sack, J; Flück, CE and Miller, WL. Diversity and function of mutations in P450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis. Am J Hum Genet 76: 729-749 (2005).


2004

18. Pandey, AV; Flück, CE; Huang, N; Tajima, T; Fuijeda, K and Miller, WL. P450 oxidoreductase deficiency: A new disorder of steroidogenesis affecting all microsomal P450 enzymes. Endocrine Res 30: 881-888 (2004).

17. Miller WL, Huang N, Flück CE and Pandey AV. P450 oxidoreductase deficiency. Lancet 364: 1663 (2004).

16. Flück CE, Tajima T, Pandey AV, Arlt W, Okuhara K, Verge CF, Jabs EW, Mendonca BB, Fujieda K and Miller WL. Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome. Nature Genetics 36: 228-30 (2004).


2003

15. Pandey AV; Babbarwal VK; Okoyeh JN; Joshi RM; Puri SK; Singh RL and Chauhan VS. Hemozoin formation in malaria: a two-step process involving histidine-rich proteins and lipids. Biochem Biophys Res Commun. 308:736-743 (2003).

14. Pandey AV, Mellon SH and Miller WL. Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17.J Biol Chem. 278:2837-2844 (2003).



2002

13. Pandey, AV and Chauhan VS. New targets for malaria drug development. In Multi-Drug Resistance.(Mahajan, RC, Therwath, A. Edts), CRC Press LLC, Boca Rattan, FL 147-156, (2002).


2001

12. Pandey AV; Bisht H; Babbarwal VK; Srivastava J; Pandey KC and Chauhan VS. Mechanism of malarial haem detoxification inhibition by chloroquine. Biochem J. 355:333-338 (2001).


2000

11. Pandey, AV and Chauhan, VS New Drug targets in Malaria. In Emerging and re-emerging infections. Narosa Publications pp 122-127 (2000).


1999

10. Pandey, AV; Tekwani, BL; Singh, RL and Chauhan VS. Artemisinin, an endoperoxide antimalarial, disrupts the hemoglobin catabolism and heme detoxification systems in malarial parasite. J Biol Chem. 274:19383-19388 (1999).

9. Pandey AV; Singh N; Tekwani BL; Puri SK and Chauhan VS. Assay of beta-hematin formation by malaria parasite. J Pharm Biomed Anal. 20:203-207 (1999).

8. Pandey AV; Joshi SK; Tekwani BL and Chauhan VS. A colorimetric assay for heme in biological samples using 96-well plates. Anal Biochem. 268:159-161 (1999).



1998

7. Pandey, AV and Chauhan, VS Heme polymerisation by malarial parasite : A potential target for antimalarial drug development. Current Sc. 75:911-918 (1998).


1997

6. Pandey AV; Joshi R; Tekwani BL; Singh RL and Chauhan VS. Synthetic peptides corresponding to a repetitive sequence of malarial histidine rich protein bind haem and inhibit haemozoin formation in vitro. Mol Biochem Parasitol. 90:281-287 (1997).


5. Pandey AV and Tekwani BL. Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials. FEBS Lett. 1997 402:236-240 (1997).


1996

4. Pandey AV and Tekwani BL. Identification and quantification of haemozoin: Some additional facts. Parasitol Today. 12:370 (1996).

3. Pandey AV and Tekwani BL. Formation of haemozoin/beta-haematin under physiological conditions is not spontaneous. FEBS Lett. 393:189-193 (1996).

2. Pandey, AV; Srivastava, P; Tekwani, BL and Pandey, VC Effect of Plasmodium yoelii infection on constitutive and phenobarbitone inducible mixed function oxidase system of mice. J. Parasit. Dis. 20:141-144 (1996).


1995

1. Pandey, AV, Tekwani, BL and Pandey, VC Characterisation of hemozoin from liver and spleen of mice infected with Plasmodium yoelii, a rodent malaria parasite. Biomed. Res. 16:115-120 (1995).